Paris Saint-Germain will be without Neymar when they face Rennes in Ligue 1 on Sunday.
Thomas Tuchel’s team top the table by 10 points, with three games in hand on second-placed Lille, ahead of Sunday’s home match at the Parc des Princes.
However, the injury to Brazil international Neymar is causing some concern after the forward suffered a recurrence of a foot issue in Wednesday’s Coupe de France clash with Strasbourg.
Manchester United face the Ligue 1 holders in the Champions League last 16 first leg clash at Old Trafford on Tuesday, February 12 and Neymar faces a race against time to be fit for that game.
Tuchel told a press conference: “It’s still a bit early to comment on Neymar.
“We’ll follow developments in the next few days but I’m very sad for him. I hope he can come back soon.”
Midfielder Marco Verratti is another absentee with an ankle strain and Tuchel added: “The fact that Neymar and Marco are injured is a sad situation for us.
“It’s always hard to lose key players like them. But we are mentally strong and we have other talented players who can do the job.
“We need to find solutions collectively to keep winning.”
However, defender Presnel Kimpembe, absent since the beginning of the year, could figure against Rennes after proving his fitness in training.
Tuchel said: “It will be a tough match against Rennes. They have good potential in defence and attack, we must be very careful.”
He was reluctant to look ahead to the upcoming visit to United, adding: “We remain focused on this match. The meeting against United is not for now, we have time.”